The individuals received a new group of tubs every 12 weeks. Unused margarine tubs had been returned. An objective way of measuring adherence was acquired by determining the degrees of fatty acids in plasma cholesteryl esters in random subgroups of approximately 800 sufferers at baseline and after 20 and 40 months of intervention.16 At baseline, anthropometric actions were assessed, and blood pressure and heart rate were measured. In addition, nonfasting blood samples were acquired for the measurement of serum lipid and plasma sugar levels.16 Demographic factors, lifestyle characteristics, and medicine and medical histories had been assessed with the use of questionnaires.1 mmol per liter [200.0 mg per deciliter] in the case of nonfasting patients).Each patient’s clinical status was recorded by using the altered Rankin scale. Subarachnoid hemorrhage was identified by means of either computed tomographic imaging or lumbar puncture or was documented at autopsy . A diagnosis of aneurysm was based on pictures obtained through magnetic resonance angiography, high-quality three-dimensional CT angiography, or digital-subtraction or conventional angiography. For computer images , how big is the aneurysm was measured with the use of digital data. In the case of digital-subtraction or conventional angiographic machines which were not built with size-measurement devices, the 1-yen coin method was utilized.